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Early Bird Price ends in exactly.. Andrew Darius. When I offer a bonus on my offers my audience can clearly see how many bonuses are left so there is no confusion. Sam Robinson. Internet Marketer. Josh Ratta. In Motion Tech. All these applications prompted me to develop the software EASYPOP, an individual-based model that simulates neutral loci datasets under a very broad range of conditions. For haploid organisms, the proportion of clonal and sexual reproduction recombination can be set, whereas for diploid organisms with one sex, the proportion of selfing can also be selected.
For diploid organisms with two sexes, there is the choice between hermaphrodites or sexuals. For hermaphrodites, the proportion of selfing can be set, whereas for sexuals complex breeding structures can be simulated e. Numbers of individuals males and females can be set independently for each population and dispersal is sex specific. Various migration models are implemented, such as the two-dimensional stepping stone or hierarchical island model. In addition, there is an isolation by distance option that works with the coordinates of the populations in any number of dimensions.
The migration model and migration rates can be modified after a certain number of generations. This later option allows us to explore the genetic consequences of a modification of the migration pattern or to impose a bottleneck on a population. There are also several mutation models implemented, which are oriented toward the simulation of microsatellite loci.
Mutation rates, mutation models, and the maximal number of allelic states can be set individually for each locus. Genotypes are real multilocus; that is, genotypes are not independent replicates over loci. Most parameters are limited only by the memory of the computer. However, the number of possible allelic states and the number of populations are limited to and 10,, respectively.
It is possible to run up to 99 independent replicates. The program works with probabilities e. EASYPOP has been debugged as carefully as possible by testing simulation results against analytical expectations in all cases where they could be computed. Some of these tests can be found in Balloux et al. The input consists only of the parameters of the simulation chosen by the user.
The outputs of the program are the multilocus genotypes after a given number of generations. This allows for direct analysis of the results using the mentioned population genetics packages. An additional output file giving the number of alleles, Nei and Chesser's unbiased heterozygosities, and F statistics for each 10th generation is provided.
This file can be used to follow these quantities over time. The C source code can be obtained by e-mailing: francois. It is a pleasure to thank Jean Lehman who introduced me to programming. Small business can use a free POS system to take payment in their store, online, at events, or wherever they make sales. Includes answers to common questions.
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